by National Aeronautics and Space Administration, Scientific and Technical Information Branch, For sale by the National Technical Information Service] in Washington, D.C, [Springfield, Va .
Written in English
|Statement||Mark E. Koslin and Frederick A. White ; prepared for Langley Research Center under grant NSG-1360.|
|Series||NASA contractor report -- NASA CR-3165.|
|Contributions||White, Frederick Andrew, 1918-, United States. National Aeronautics and Space Administration. Scientific and Technical Information Branch., Langley Research Center.|
|The Physical Object|
|Pagination||vi,  p. :|
|Number of Pages||105|
Characterization of Impurities and Degradants Using Mass Spectrometry examines how mass spectrometry (MS) can be applied to improve the drug development process and get drugs approved more quickly. This book looks at spectrometry with an overview of its capabilities, and then guides the reader on techniques as they relate to the analysis of impurities and degradants, showing why these Format: Hardcover. Diffusion and phase change characterization by mass spectrometry. By M. E. Koslin and F. A. White. Abstract. The high temperature diffusion of trace elements in metals and alloys was investigated. Measurements were made by high sensitivity mass spectrometry in which individual atoms were detected, and quantitative data was obtained for Author: M. E. Koslin and F. A. White. Diffusion and phase change characterization by mass spectrometry / (Washington, D.C.: National Aeronautics and Space Administration, Scientific and Technical Information Branch; [Springfield, Va.: For sale by the National Technical Information Service], ), by Mark E. Koslin, Frederick Andrew White, Langley Research Center, and United States. Mass Spectrometry: Principles and Applications, Third Edition. Edmond de Hoffmann, UniversitÃ© Catholique de Louvain, Belgium and Vincent Stroobant, Ludwig Institute for Cancer Research, Brussels Branch, Belgium. Mass Spectrometry, Third Edition provides students with a complete overview of the principles, theories and key applications of modern mass by:
This study describes a novel approach for monitoring noncovalent interactions in solution by electrospray mass spectrometry (ESI-MS). The technique is based on measurements of analyte diffusion in solution. Diffusion coefficients of a target macromolecule and a potential low molecular weight binding partner are determined by measuring the spread of an initially sharp boundary between Cited by: In this work, thermal and phase stability of primary CoSb 3 skutterudite prepared by different procedures were investigated using thermal analysis and Knudsen effusion mass spectrometry performed on a Netzsch STA CD/3//5/G apparatus, a specially-adapted type of the commercial STA CD - QMS /5 Skimmer Coupling Instrument. Results Author: Nathan Jacobson, Dietmar Kobertz, Dmitry Sergeev. This two-volume book provides an overview of physical techniques used to characterize the structure of solid materials, on the one hand, and to investigate the reactivity of their surface, on the other. Therefore this book is a must-have for anyone working in fields related to surface reactivity. Mass spectrometry has been applied to identify and structurally elucidate AGEs. Here, we report on the identification of AGE- peptides and AGE-precursors based on relative mass changes as a result.
Advances in mass spectrometry. Mass spectrometers continue to evolve, propelled by demands from the proteomics community for increased sensitivity, higher mass accuracy and resolving power, improved duty cycle and more efficient fragmentation of peptides in MS/MS. Electrospray ionisation MS/MS has been used for several years for peptide by: Mass spectrometry 1. Solubilize digested peptide samples into a working volume of HPLC grade 5% acetonitrile/% formic acid for injection into the HPLC autosampler, typically µl volumes are reasonable. 2. Resulting peptides are injected onto a 3-µm C 18 reversed-phase (RP) resin column (Acclaim PepMap, 75 µm × 15 cm). In this work, reversed-phase liquid chromatography and mass spectrometry were used to characterize four of the most abundant thiol modifiers on recombinant proteins secreted from E. coli BL21 (DE3. Tandem Mass Spectrometry Molecular Characterization. This book serves multiple groups of audiences; professional, graduate students and general readers interested in the use of modern mass spectrometry in solving critical questions of chemical and biological sciences. The areas covered include the analysis of drugs, metabolites, carbohydrates.